产品详情 |
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Antigenic Specificity | CCR5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 100 ul |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to CCR5.C-C chemokine receptor type 5 (CCR5) is a multi-pass membrane protein that belongs to the Gproteincoupled receptor 1 family. It is a receptor for a number of inflammatory CC-chemokinesincluding MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasingthe intracellular calcium ion level. It may play a role in the control of granulocytic lineage proliferationor differentiation. CCR5 acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.Genetic variation in CCR5 is associated with susceptibility to diabetes mellitus insulin-dependent type22 (IDDM22). |
Immunogen | middle region of human CCR5 |
Other Names | CCR5,CC chemokine receptor type 5,CC CKR5,CCCKR5,CCR5,CCR5,CHEMR13,HIV1 fusioncoreceptor,CD195,CMKBR5 |
Gene, Accession # | UniProt: P51681 |
Catalog # | orb67199 |
Price | |
Order / More Info | CCR5 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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