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| Product Name | CLCF1, 28-225aa, Human, His tag, E.coli (Denatured) |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid. 20mM sodium citrate (pH 3.5), 0.4M urea, 10% glycerol. CLCF1, also known as cardiotrophin-like cytokine factor 1, belongs to the interleukin 6 family of cytokines, which are involved in cell signaling through phosphorylation of gp130. CLCF1 has a sequence of 225-amino acids with a 27-aa signal peptide, a molecular mass of 22 kDa in mature form, and the highest homology to cardiotrophin-1 and ciliary neurotrophic factor. CLCF1 can be actively secreted from cells by forming a complex with soluble type I CRLF1 or soluble CNTFR. Defects in CLCF1 cause cold-induced sweating syndrome 2 (CISS2). This syndrome is characterized by a profuse sweating after exposure to cold as well as congenital physical abnormalities of the head and spine. |
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| Size | 0.5mg, 100ug, 20ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Cardiotrophin-like cytokine factor 1, BSF-3, BSF3, CISS2, CLC, NNT-1, NNT1, NR6 |
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| Gene, Accession, CAS # | NP 037378 |
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| Catalog # | ATGP1179 |
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| Order / More Info | CLCF1, 28-225aa, Human, His tag, E.coli (Denatured) from ATGen |
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| Product Specific References | n/a |
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