| 产品详情 |
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| Product Name | Vatalanib Dihydrochloride |
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| Description | Purity >98% by HPLC. Cell-permeable. An inhibitor of the VEGFR tyrosine kinases VEGFR-1 (Flt-1, IC50 = 77 nM) and VEGFR-2 (FLK-1/KDR, IC50 = 37 nM), with slightly higher potency against the latter. At higher concentrations, other tyrosine kinases are also inhibited, including PDGFR-Beta (IC50 = 580 nM), c-KIT (IC50 = 730 nM), FLT-4 (IC50 = 660 nM) and c-FMS (IC50 = 1.4 µM). On the other hand, vatalanib is not active against the EGFR, c-SRC, v-ABL, and protein kinase Ca (IC50 > 10 µM). |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CGP-79787, PTK 787, ZK222584 |
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| Gene, Accession, CAS # | CAS: 212141-51-0 |
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| Catalog # | LS-H2645 |
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| Price | |
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| Order / More Info | Vatalanib Dihydrochloride from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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