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Product Name | CARD18, 1-90aa, Human, His tag, E.coli |
Description | Purity: > 95% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT,10% glycerol, 0.1M NaCl . Caspase recruitment domain-containing protein 18, also known as CARD18, is a member of the death-domain-fold superfamily that is induced by proinflammatory stimuli. It consists essentially only of a CARD, inhibits generation of IL-1b by interacting with caspase-1 and preventing association with RIP 2. The association of CARD18 with caspase-1 is facilitated by the charge-charge interactions between the prodomain of caspase-1 and the surface charge of CARD18. Recombinant human CARD18 proetin, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Size | 250ug, 50ug, 10ug |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | Caspase recruitment domain-containing protein 18, ICEBERG, pseudo-ICE, uNQ5804 |
Gene, Accession, CAS # | NP 067546 |
Catalog # | ATGP1460 |
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Order / More Info | CARD18, 1-90aa, Human, His tag, E.coli from ATGen |
Product Specific References | n/a |
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