| 产品详情 |
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| Product Name | Mouse PTEN (aa 252-269) Synthetic Peptide |
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| Description | Mouse PTEN (aa 252-269) Synthetic Peptide. PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The PTEN gene is a phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. PTEN negatively regulates intracellular levels of phosphatidylinositol-3, 4, 5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. PTEN plays a role as a key modulator of the AKT-mTOR signaling pathway contr |
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| Size | 50 µg |
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| Concentration | lyophilized |
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| Applications | Control: Assay Dependent |
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| Other Names | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, MMAC1, TEP1, Phosphatase and tensin homolog |
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| Gene, Accession, CAS # | Entrez: 19211; Uniprot: O08586 |
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| Catalog # | PEP-284 |
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| Price | |
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| Order / More Info | Mouse PTEN (aa 252-269) Synthetic Peptide from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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