| 产品详情 |
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| Antigenic Specificity | CD80 (B7-1) |
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| Clone | 16-10A1 |
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| Host Species | Armenian Hamster |
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| Reactive Species | canine, mouse, porcine |
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| Isotype | IgG |
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| Format | eFluor 450 conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.25 µg/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD80 (B7-1) Monoclonal Antibody (16-10A1), eFluor 450, eBioscience™. CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response. |
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| Immunogen | n/a |
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| Other Names | B7-1, B7.1, Cd28l, Ly-53, Ly53, MIC17, TS/A-1, LAB7, B7.1, CD28LG, CD28LG1 |
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| Gene, Accession # | Entrez: 12519, 397161, 403765; Uniprot: Q00609 |
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| Catalog # | 48-0801-82 |
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| Order / More Info | CD80 (B7-1) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 18719016, 22590614, 23300949, 24253609, 24384074, 25289030, 25704819, 26091088, 26986456, 26998006, 27352928, 28240301, 28411140, 28440413, 28819104, 28901417, 29163499 |
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