| 产品详情 |
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| Antigenic Specificity | Btk |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 10 µg/mL, Immunofluorescence: 10 µg/mL, Western Blot: 0.5-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Btk Polyclonal Antibody. Bruton's tyrosine kinase (BTK) was initially identified as a member of the src family for protein-tyrosine kinases that was involved in X-linked a-gamma-globulinaemia, and has since been shown to involved in a number of signaling pathways in hemapoietic lineage. It has recently been shown to interact with members of the toll-like receptor (TLR) family such as TLR4, 6, 8, and 9. The TLRs are critical molecules in both the innate and adaptive immunity and can recognize diverse microbial pathogens. BTK has also been shown to interact with key proteins involved in TLR4 signal transduction such as MyD88, TIRAP, and IRAK, but not TRAF-6, suggesting that BTK is involved in lipopolysaccharide signal transduction. |
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| Immunogen | n/a |
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| Other Names | RP1-164F3.2, AGMX1, AT, ATK, BPK, IMD1, PSCTK1, XLA; B-cell progenitor kinase; agammaglobulinaemia tyrosine kinase; dominant-negative kinase-deficient Brutons tyrosine kinase; tyrosine-protein kinase BTK; tyrosine-protein kinase BTK isoform (lacking exon 14) |
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| Gene, Accession # | Entrez: 12229, 695; Uniprot: P35991, Q06187 |
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| Catalog # | PA5-20085 |
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| Price | |
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| Order / More Info | Btk Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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