产品详情 |
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Antigenic Specificity | BTLA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Western Blot: 3-5 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BTLA Polyclonal Antibody. B and T lymphocyte attenuator (BTLA) is a 289 amino acid recently identified inhibitory receptor that provides crucial activating or attenuating signals for T cells. It is a third member of co-inhibitory receptors of the CD28 immunoglobulin superfamily with similarities to (CTLA)-4 and (PD)-1 and interacts with a B7 homolog, B7H4. BTLA is constitutively expressed on most CD4+ and CD8+ T cells and its expression progressively decreases upon T cell activation. It remains expressed on Th1 cells but not Th2 cells. BTLA is a unique co-receptor which interacts with the tumor necrosis factor receptor superfamily member herpesvirus entry mediator (HVEM) and this interaction is an important pathway regulating lymphocyte act |
Immunogen | n/a |
Other Names | BTLA1, CD272, B and T lymphocyte attenuator, B- and T-lymphocyte attenuator, B- and T-lymphocyte-associated protein |
Gene, Accession # | Entrez: 151888, 208154; Uniprot: Q7TSA3, Q7Z6A9 |
Catalog # | PA5-23147 |
Price | |
Order / More Info | BTLA Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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