| 产品详情 |
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| Antigenic Specificity | CD86 (B7-2) |
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| Clone | GL1 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, kappa |
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| Format | eFluor 450 conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.25 µg/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD86 (B7-2) Monoclonal Antibody (GL1), eFluor 450, eBioscience™. CD86 is one of two ligands (the other CD80) for CTLA4 and CD28. CD86 acts as costimulatory molecule in eliciting T-cell help during antigen presentation. Antigen presentation in the absence of sufficient co-stimulation involving CD86/CD80 can induce tolerance. CD80 appears to play a role distinct from CD80 in T helper cell differentiation. CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily. The CD86 protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal |
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| Immunogen | n/a |
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| Other Names | B7-2, B7.2, B70, CD28LG2, LAB72, MGC34413, B-lymphocyte activation antigen B7-2, B-lymphocyte antigen B7-2, B7-2 antigen, BU63, CD28 antigen ligand 2 |
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| Gene, Accession # | Entrez: 12524; Uniprot: P42082 |
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| Catalog # | 48-0862-82 |
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| Order / More Info | CD86 (B7-2) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 18604213, 22590614, 23300949, 24253609, 24384074, 25215539, 25289030, 25485616, 26096149, 26265369, 26325217, 26872029, 26986456, 26998006, 27761470, 28018179, 28901417, 29163499, 29546785 |
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