产品详情 |
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Antigenic Specificity | CD86 (B7-2) |
Clone | GL1 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, kappa |
Format | phycoerythrin (PE) conjugate |
Size | 50 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.125 µg/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD86 (B7-2) Monoclonal Antibody (GL1), PE, eBioscience™. CD86 is one of two ligands (the other CD80) for CTLA4 and CD28. CD86 acts as costimulatory molecule in eliciting T-cell help during antigen presentation. Antigen presentation in the absence of sufficient co-stimulation involving CD86/CD80 can induce tolerance. CD80 appears to play a role distinct from CD80 in T helper cell differentiation. CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily. The CD86 protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal for acti |
Immunogen | n/a |
Other Names | B7-2, B7.2, B70, CD28LG2, LAB72, MGC34413, B-lymphocyte activation antigen B7-2, B-lymphocyte antigen B7-2, B7-2 antigen, BU63, CD28 antigen ligand 2 |
Gene, Accession # | Entrez: 12524; Uniprot: P42082 |
Catalog # | 12-0862-81 |
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Order / More Info | CD86 (B7-2) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 16709845, 17629367, 17709420, 18337479, 18566404, 18604213, 18757428, 19109151, 19440334, 19458089, 19727134, 19805617, 20065112, 20109461, 20453106, 20483781, 20538992, 20566414, 20644175, 20719903, 20817863, 21178008, 21233299, 21435448, 21444662, 21538316, 21551361, 21566096, 21832165, 21925110, 22273579, 22354374, 22467656, 22590614, 23299799, 23300949, 23392255, 23447566, 23630120, 23715623, 23825947, 23843936, 24018532, 24253609, 24270517, 24384074, 24401681, 24465481, 24466057, 24554775, 24573741, 24760891, 24763671, 25237205, 25289030, 25296026, 25485616, 25980009, 26096149, 26114112, 26265369, 26325217, 26371125, 26841680, 26843325, 26872029, 26885373, 26986456, 26998006, 27057467, 27062545, 27278624, 27471636, 27736880, 27761470, 28018179, 28239619, 28411140, 28479366, 28901417, 29163499, 29198913, 29546785, 29867472 |
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