| 产品详情 |
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| Antigenic Specificity | CD86 (B7-2) |
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| Clone | IT2.2 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b, kappa |
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| Format | unconjugated, functional grade |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.25 µg/test, Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD86 (B7-2) Monoclonal Antibody (IT2.2), Functional Grade, eBioscience™. CD86 is one of two ligands (the other CD80) for CTLA4 and CD28. CD86 acts as costimulatory molecule in eliciting T-cell help during antigen presentation. Antigen presentation in the absence of sufficient co-stimulation involving CD86/CD80 can induce tolerance. CD80 appears to play a role distinct from CD80 in T helper cell differentiation. CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily. The CD86 protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory |
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| Immunogen | n/a |
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| Other Names | B7-2, B7.2, B70, CD28LG2, LAB72, MGC34413, B-lymphocyte activation antigen B7-2, B-lymphocyte antigen B7-2, B7-2 antigen, BU63, CD28 antigen ligand 2 |
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| Gene, Accession # | Entrez: 942; Uniprot: P42081 |
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| Catalog # | 16-0869-85 |
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| Price | |
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| Order / More Info | CD86 (B7-2) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 17709420, 19017976, 25187656, 27354564, 28810658, 28955836 |
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