| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD86 (B7-2) |
|---|
| Clone | IT2.2 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG2b, kappa |
|---|
| Format | PE-Cyanine7 conjugate |
|---|
| Size | 25 Tests |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry: 5 µL (0.125 µg)/test |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CD86 (B7-2) Monoclonal Antibody (IT2.2), PE-Cyanine7, eBioscience™. CD86 is one of two ligands (the other CD80) for CTLA4 and CD28. CD86 acts as costimulatory molecule in eliciting T-cell help during antigen presentation. Antigen presentation in the absence of sufficient co-stimulation involving CD86/CD80 can induce tolerance. CD80 appears to play a role distinct from CD80 in T helper cell differentiation. CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily. The CD86 protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory sign |
|---|
| Immunogen | n/a |
|---|
| Other Names | B7-2, B7.2, B70, CD28LG2, LAB72, MGC34413, B-lymphocyte activation antigen B7-2, B-lymphocyte antigen B7-2, B7-2 antigen, BU63, CD28 antigen ligand 2 |
|---|
| Gene, Accession # | Entrez: 942; Uniprot: P42081 |
|---|
| Catalog # | 25-0869-41 |
|---|
| Price | |
|---|
| Order / More Info | CD86 (B7-2) Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | PubMed: 27354564, 28810658 |
|---|
| 产品资料 |
|
|