产品详情 |
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Antigenic Specificity | CD86 (B7-2) |
Clone | IT2.2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, kappa |
Format | Super Bright 645 conjugate |
Size | 25 Tests |
Concentration | n/a |
Applications | Flow Cytometry: 5 µL (0.25 µg)/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD86 (B7-2) Monoclonal Antibody (IT2.2), Super Bright 645, eBioscience™. CD86 is one of two ligands (the other CD80) for CTLA4 and CD28. CD86 acts as costimulatory molecule in eliciting T-cell help during antigen presentation. Antigen presentation in the absence of sufficient co-stimulation involving CD86/CD80 can induce tolerance. CD80 appears to play a role distinct from CD80 in T helper cell differentiation. CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily. The CD86 protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | Entrez: 942; Uniprot: P42081 |
Catalog # | 64-0869-41 |
Price | |
Order / More Info | CD86 (B7-2) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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