产品详情 |
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Antigenic Specificity | ESRRB |
Clone | 9H8L3 |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry: 1:100, Immunofluorescence: 1:100 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ESRRB Antibody (9H8L3), ABfinity™ Rabbit Monoclonal. ESRRB (steroid hormone receptor ERR2) plays a role in the maintenance of self-renewal and pluripotency of embryonic and trophoblast stem cells through different signaling pathways including FGF signaling pathway and Wnt signaling pathways. Upon FGF signaling pathway activation ESRRB interacts with KDM1A by directly binding to enhancer sites of ELF5 and EOMES and activates their transcription leading to self-renewal of trophoblast stem cells. ESSRB also regulates expression of multiple rod-specific genes and is required for survival of this cell type. Defects in the gene can cause deafness, autosomal recessive, 35 (DFNB35). |
Immunogen | n/a |
Other Names | ERRB2, ESRL2, NR3B2 |
Gene, Accession # | Entrez: 2103; Uniprot: O95718 |
Catalog # | 703237 |
Price | |
Order / More Info | ESRRB Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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