| 产品详情 |
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| Antigenic Specificity | PEX19 |
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| Clone | GT554 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:1000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PEX19 Monoclonal Antibody (GT554). Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53. |
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| Immunogen | n/a |
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| Other Names | D1S2223E, HK33, PMP1, PMPI, PXF, PXMP1, 33 kDa housekeeping protein, housekeeping gene, 33kD, peroxin-19, peroxisomal farnesylated protein |
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| Gene, Accession # | Entrez: 19298, 5824; Uniprot: P40855, Q8VCI5 |
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| Catalog # | MA5-17266 |
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| Price | |
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| Order / More Info | PEX19 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 28281558 |
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