产品详情 |
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Antigenic Specificity | ERK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 20 µL |
Concentration | n/a |
Applications | Immunohistochemistry: 1:20-1:100, Western Blot: 1:1,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ERK1 Polyclonal Antibody. ERK1 is widely expressed and involved in the regulation of meiosis, mitosis, and post-mitotic functions in differentiated cells. Many different stimuli, including growth factors, cytokines, virus infection, ligands for heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors and transforming agents, activate the ERK1 and ERK2 pathways. When growth factors bind to the receptor tyrosine kinase, Ras interacts with Raf, the serine/threonine protein kinase and activates it as well. Once actived, Raf phosphorylates serine residue in 2 further kinases, MEK1/2, which in turn phosphorylates tyrosine/threonine in extracellular-signal regulated kinase (ERK) 1/2. Upon activation, the ERKs either phosphor |
Immunogen | n/a |
Other Names | MAPK3. mitogen-activated protein kinase 3 . HGNC:6877. P44ERK1. P44MAPK. PRKM3. protein kinase, mitogen-activated 3 (MAP kinase 3 p44) |
Gene, Accession # | Entrez: 5595; Uniprot: P27361 |
Catalog # | A302-060A-T |
Price | |
Order / More Info | ERK1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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