| 产品详情 |
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| Antigenic Specificity | ERK1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 50 ug |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ERK1 Polyclonal Antibody. ERK1 is widely expressed and involved in the regulation of meiosis, mitosis, and post-mitotic functions in differentiated cells. Many different stimuli, including growth factors, cytokines, virus infection, ligands for heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors and transforming agents, activate the ERK1 and ERK2 pathways. When growth factors bind to the receptor tyrosine kinase, Ras interacts with Raf, the serine/threonine protein kinase and activates it as well. Once actived, Raf phosphorylates serine residue in 2 further kinases, MEK1/2, which in turn phosphorylates tyrosine/threonine in extracellular-signal regulated kinase (ERK) 1/2. Upon activation, the ERKs either phosphor |
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| Immunogen | n/a |
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| Other Names | ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK, MAP kinase 1, MAP kinase 3, MAP kinase isoform p44, MAPK 1, extracellular signal-regulated kinase 1, extracellular signal-related kinase 1, insulin-stimulated MAP2 kinase, microtubule-associated protein 2 kinase, mitogen-activated protein kinase 1 |
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| Gene, Accession # | Entrez: 5595; Uniprot: P27361 |
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| Catalog # | PA5-32912 |
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| Price | |
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| Order / More Info | ERK1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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