产品详情 |
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Antigenic Specificity | ERK5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 400 µL |
Concentration | n/a |
Applications | Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ERK5 Polyclonal Antibody. MEK5 and ERK5, a member of the MAP kinase subfamily of the Ser/Thr protein kinases, interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. ERK5 is activated by tyrosine and threonine phosphorylation It is expressed in many adult tissues, abundantly in heart, placenta, lung, kidney and skeletal muscle, but is not detectable in liver. The second proline-rich region may interact with actin targeting the kinase to a specific location in the cell. ERK5 is autophosphorylated on threonine and tyrosine residues when the C-terminal part of the kinase, which could have a regulatory role, is absent. |
Immunogen | n/a |
Other Names | Extracellular signal-regulated kinase 5, Mitogen-activated protein kinase 7 |
Gene, Accession # | Entrez: 5598; Uniprot: Q13164 |
Catalog # | PA5-14416 |
Price | |
Order / More Info | ERK5 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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