产品名称 PTPN7 Antibody from INVITROGEN ANTIBODIES
产品货号 MA5-17227
产品价格 现货询价,电话:010-67529703
产品规格 100 µL
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityPTPN7
CloneAFPK32
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatpurified
Size100 µL
Concentrationn/a
ApplicationsELISA: Assay Dependent, Western Blot: 1:5000
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DescriptionPTPN7 Monoclonal Antibody (AFPK32). Hematopoietic tyrosine phosphatase (HePTP, PTPN7) belongs to a subgroup of PTPases with two other members, STEP and PCPTP1. HePTP is a 38 kDa class I non-receptor protein tyrosine phosphatase (PTP) that is strongly expressed in T cells. The protein consists of a short, amino-terminal extension that contains a conserved 16-amino acid kinase interaction motif (KIM) and a carboxy-terminal protein tyrosine phosphatase domain. HePTP binds the MAPK family kinases, Erk1/2 and p38 via KIM. Erk phosphorylates HePTP (at Thr45 and Ser72) and HePTP dephosphorylates Erk (at Tyr185). HePTP is phosphorylated at Ser23 within the KIM by PKA in T cells. This phosphorylation results in dissociation of the HePTP/ERK2 complex
Immunogenn/a
Other NamesTyrosine-protein phosphatase non-receptor type 7; Protein-tyrosine phosphatase LC-PTP; Hematopoietic protein-tyrosine phosphatase; LPTP; HEPTP; PTPNI; BPTP-4; LC-PTP
Gene, Accession #Entrez: 5778; Uniprot: P35236
Catalog #MA5-17227
Price
Order / More InfoPTPN7 Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
产品资料