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| Product Name | CRHR1, Recombinant, Human, aa23-121, His-Tag (Corticotropin-releasing Factor Receptor 1) |
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| Description | Purity ~90% (SDS-PAGE). G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli. Source: Recombinant protein corresponding to aa23-121 from human CRHR1, fused to His-Tag at N-terminal, expressed in Yeast. Molecular Weight: ~13.1kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Corticotropin-releasing hormone receptor 1, CRH-R-1, CRH-R1 |
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| Gene, Accession, CAS # | SwissProt: P34998 |
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| Catalog # | 372865 |
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| Order / More Info | CRHR1, Recombinant, Human, aa23-121, His-Tag (Corticotropin-releasing Factor Receptor 1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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