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| Product Name | MD-2, Control Peptide (MD-2 Protein, ESOP1, ESOP-1, Lymphocyte Antigen 96, LY96) |
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| Description | Sequence: 13aa near the middle region of human MD-2 (1). MD-2 enables TLR4 to respond to a wide variety of LPS partial structures, Gram-negative bacteria, and Gram-positive lipoteichoic acid, but not to Gram-positive bacteria, peptidoglycan, and lipopeptide. Toll Like Receptors (TLRs) are the mammalian homologues of the Drosophila Toll protein, which is a transmembrane receptor. TLR2 and TLR4 are essential components for recognition of distinct bacterial cell wall components. TLRs have been shown to participate in the recognition of pathogens by the innate immune system. The cytoplasmic domain of TLR2 can form functional pairs with TLR6 or TLR1, and this interaction leads to cytokine induction. TLR6, TLR2, and TLR1 are recruited to macrophage phagosomes that contain IgG-coated erythrocytes that do not display microbial components. TLRs sample the contents of the phagosome independent of the nature of the contents, and can establish a combinatorial repertoire to discriminate among the l |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | M2767-20D |
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| Order / More Info | MD-2, Control Peptide (MD-2 Protein, ESOP1, ESOP-1, Lymphocyte Antigen 96, LY96) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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