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| Product Name | MDK, Recombinant, Human, aa21-143, GST-Tag (Midkine) |
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| Description | Purity ~90% (SDS-PAGE). Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development. Source: Recombinant protein corresponding to aa21-143 from human Midkine, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~40.4kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Amphiregulin-associated protein, ARAP Midgestation and kidney protein, Neurite outgrowth-promoting factor 2, Neurite outgrowth-promoting protein |
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| Gene, Accession, CAS # | SwissProt: P21741 |
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| Catalog # | 374178 |
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| Order / More Info | MDK, Recombinant, Human, aa21-143, GST-Tag (Midkine) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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