| 产品详情 |
| Edit |   |
|---|
| Product Name | AMIGO2, Recombinant, Human, Fc Chimera (Amphoterin-induced Gene, ORF 2, Alivin-1) |
|---|
| Description | Purity ~90% (SDS-PAGE). AMIGO2 (amphoterininduced gene and ORF 2), also known as DEGA and Alivin1, is an approximately 65kD transmembrane cell adhesion protein. It belongs to a family of leucinerich repeat (LRR) containing proteins that play various roles in nervous system development and function (1, 2). Mature human AMIGO2 consists of a 359aa extracellular domain (ECD) with six LRRs flanked by single LRRNT and LRRCT domains, followed by one immunoglobulinlike domain, a 21aa transmembrane segment, and a 103aa cytoplasmic domain (35). Within the ECD, human AMIGO2 shares 89% and 87% aa sequence identity with mouse and rat AMIGO2, respectively. AMIGO2 forms homodimers as well as heterodimers with the related AMIGO and AMIGO3 molecules (3, 6). Within the nervous system, AMIGO2 is transcribed in the cerebrum, hypothalamus, olfactory bulb, retina, hippocampus (pyramidal cells), and cerebellum (granule neurons and Purkinje cells) (3, 4, 7). It is also expressed in the liver, lung, testi |
|---|
| Size | 50ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | SwissProt: Q86SJ2 |
|---|
| Catalog # | 167624 |
|---|
| Price | |
|---|
| Order / More Info | AMIGO2, Recombinant, Human, Fc Chimera (Amphoterin-induced Gene, ORF 2, Alivin-1) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|