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| Product Name | Fibroblast growth factor 21, aa29-209, Recombinant, Human (FGF-21) |
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| Description | Purity ≥ 90% (SDS-PAGE). FGF-21 is a unique member of FGF super family that is reported to be primarily produced by the liver. FGF-21 has recently been shown to have beneficial effects on a variety of metabolic parameters, including glucose and lipid metabolism and insulin sensitivity in animal models and is thought to exert potent antidiabetic and lipid-lowering agent of obesity and type 2 diabetes mellitus. FGF-21 activity depends on membrane protein beta Klotho that physically complexes with various FGF receptors, thus conferring them the ability to bind FGF-21 and activate downstream signaling pathways. Recombinant human FGF-21 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. Endotoxin Level: ≤ 1.0 EU per 1ug of protein (determined by LAL method) AA Sequence: MGSSHHHHHH SSGLVPRGSH MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHG |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_061986 |
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| Catalog # | F4212-93D |
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| Order / More Info | Fibroblast growth factor 21, aa29-209, Recombinant, Human (FGF-21) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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