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| Product Name | Lipopolysaccharide Binding Protein, Recombinant, Mouse (LBP, LPSBP) |
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| Description | Purity ~95% (SDS-PAGE). LBP (Lipopolysaccharide binding protein) is a 58-62kD, single-chain glycoprotein member of the BPI/LBP family, BPI/PLUNC/PSP superfamily of lipid-binding proteins (1-3). It is secreted by a number of mammalian cell types, including hepatocytes (4), gingival keratinocytes (5), intestinal Paneth cells (6), and type II Greater alveolar cells (7). LBP is considered to be a class 1 APR (acute phase reactant) that is induced upon exposure to both IL-1 and IL-6 (8). These two cytokines appear upon immune cell exposure to pathogenic microbes. Following its synthesis and release, LBP is known to interact with bacterial wall components, lipopolysaccharide/LPS/Lipid A from Gram- (Gm-) bacteria, and lipoteichoic acid/LTA from Gm+ bacteria (9-13). In the case of LPS, this interaction appears to occur both in the bacterial cell wall, and within the intercellular space, where LPS micelles naturally form following bacterial death and cell wall dissolution (14-17). LBP is posite |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_032515 |
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| Catalog # | L2525-30C |
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| Order / More Info | Lipopolysaccharide Binding Protein, Recombinant, Mouse (LBP, LPSBP) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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