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| Product Name | Cyclopamine (11-Deoxyjervine) |
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| Description | Purity ≥ 99% (HPLC). Cyclopamine blocks activation of the Hedgehog response pathway associated with mutations that either activate the proto-oncogene Smoothened (Smo) or inactivate the tumor suppressor Patched (Ptch) both of which encode multipass transmembrane proteins. Furthermore, it has been demonstrated that the inhibitory effect of cyclopamine results from its direct binding to the Smo heptahelical protein bundle. Purity: ≥ 99% |
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| Size | 25mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 11-Deoxyjervine |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C8845 |
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| Order / More Info | Cyclopamine (11-Deoxyjervine) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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