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| Product Name | ARFIP2, Recombinant, Human, aa1-341, His-Tag (Arfaptin 2) |
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| Description | Purity ~90% (SDS-PAGE). Arfaptin 2, also known as ARFIP2, is a Rac1 binding protein necessary for Rac-mediated actin polymerization and the subsequent formation of membrane ruffles and lamellipodia. ARFIP2 has also been shown to interact with the ADP ribosylation factor ARF6, a GTPase that associates with the plasma membrane and intracellular endosome vesicles, in a GTP dependent manner. Arfaptin 2 also regulates the aggregation of mutant Huntingtin protein by possibly impairing proteasome function. Expression of ARFIP2 was shown to be increased at sites of neurodegeneration. Source: Recombinant protein corresponding to aa1-341 of human ARFIP2, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~40.2kD AA |
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| Size | 100ug, 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_036534 |
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| Catalog # | 349693 |
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| Order / More Info | ARFIP2, Recombinant, Human, aa1-341, His-Tag (Arfaptin 2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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