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| Product Name | Methysergide Maleate (5-HT Serotonin Receptor Antagonsit, Methysergide Maleate, UML-491) |
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| Description | Purity ~99% (HPLC). An antagonist of the 5-HT2B (pki = 8.0-9.4) and 5-HT2C (pki = 8.6-9.1) receptor. At the 5-HT1A and some other 5-HT receptors it serves as a partial agonist. It is known to have partial agonist effects on other 5-HT receptors as well. In neuronal and platelet culture, Methysergide blocks serotonin action with an IC50 = 18uM. Originally developed in the 1960?s as a migraine/cluster headache treatment, but discontinued due to significant physiological and pyschotropic side effects. Methysergide is still actively used in research as a 5-HT2 receptor antagonist in both in vivo and in vitro experiments. Solubility: H2O Primary Target: 5-HT Molar Mass: 469.54 |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217546 |
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| Order / More Info | Methysergide Maleate (5-HT Serotonin Receptor Antagonsit, Methysergide Maleate, UML-491) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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