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| Product Name | CDK1/CyclinB1, Recombinant, Human, GST-Tag (Cell Division Control protein 1, CCNB1, CCNB) |
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| Description | Purified (~70-90%). CDK1 or Cell Division Control protein 1 is essential for the completion of START, the controlling event in the cell cycle that is required to initiate mitosis. CDK1 is a catalytic subunit of a protein kinase complex, called the M-Phase Promoting Factor that induces entry into mitosis and is universal among eukaryotes. Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis. Therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancer has also been demonstrated. Source: Recombinant protein corresponding to human CDK1/CyclinB1 fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~58kD, 75kD Specific Activity: 14nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_001786 |
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| Catalog # | 499866 |
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| Order / More Info | CDK1/CyclinB1, Recombinant, Human, GST-Tag (Cell Division Control protein 1, CCNB1, CCNB) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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