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| Product Name | Loxoribine (7-Allyl-8-oxoguanosine, RWJ 21757) |
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| Description | Purity ~97%. Guanosine analog derivatized at position N7 and C8. Very potent immunostimulatory compound that increases cytokine production. Antitumor and antiviral activity compound. Potent and selective synthetic ligand for Toll-like receptor 7 (TLR7). Co-incubation with thymidine homopolymer oligodeoxynucleotides (ODN) redirected the stimulatory effect of loxoribine away from TLR7 toward TLR8. Induces autophagy and autophagy-induced cell death in Caco-2 cells. Shows adjuvant activity to increase the effectiveness of vaccines. Formula: C13H17N5O6 Solubility: DMSO or H2O Molecular Weight: ~339.3 |
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| Size | 5mg, 25mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 207261 |
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| Order / More Info | Loxoribine (7-Allyl-8-oxoguanosine, RWJ 21757) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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