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| Product Name | DUSP3, Recombinant, Human, aa1-185, His-Tag (Dual specificity protein phosphatase 3, VHR) |
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| Description | Purity ~95% (SDS-PAGE). DUSP3 belongs to the dual specificity protein phosphatase subfamily which inactivates their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. DUSP3 negatively regulate members of the mitogen-activated protein kinase superfamily that are related to cellular proliferation and differentiation. DUSP3 is expressed in both breast and ovarian tissues and displays activity both for tyrosine-protein phosphate and serine-protein phosphate, but exhibits a strong preference toward phosphotyrosines, specifically dephosphorylates and inactivates ERK1 and ERK2. Source: Recombinant protein corresponding to aa1-185 from human DUSP3, fused to His-tag at N-terminus, expressed in E. coli. Molecular Weight: ~22.6kD (205aa, aa1-185 + NT His-Tag) Specific Activity: >1750 units/mg. One unit will hydrolyze 1nmole of p-nitrophenylphosphatate (pNPP)/minute at 37°C, pH 7.5 using 10mM of substrate. AA Sequence: MGSSHHHHHH SSGLVPRGSH MSGSFELSV |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 169958 |
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| Order / More Info | DUSP3, Recombinant, Human, aa1-185, His-Tag (Dual specificity protein phosphatase 3, VHR) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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