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| Product Name | DUT, Recombinant, Human, aa70-252, His-Tag (Deoxyuridine 5-triphosphate nucleotidohydrolase mitochondrial) |
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| Description | Purity ~90% (SDS-PAGE). DuT, also known as duTP pyrophosphatase, is a ubiquitous enzyme that functions in nucleotide metabolism. This protein, in the presence of magnesium ions, is responsible for hydrolyzing duTP to duMP and diphosphate. This reaction is important for keeping the intracellular duTP concentration low so that uracil does not become incorporated into DNA. Extensive incorporation of uracil into DNA can ultimately lead to cell death. This suggests that DuT is essential for cell viability, further implying that it is a potential target for anticancer therapy. Source: Recombinant protein corresponding to aa70-252 of human DuT, fused to His-tag at N-teminal expressed in E. coli. Molecular Weight: ~21.6kD AA |
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| Size | 100ug, 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_001020419 |
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| Catalog # | 349865 |
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| Order / More Info | DUT, Recombinant, Human, aa70-252, His-Tag (Deoxyuridine 5-triphosphate nucleotidohydrolase mitochondrial) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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