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| Product Name | TCHP, Recombinant, Human, aa1-498, His-SUMO-Tag (Trichoplein Keratin Filament-binding Protein) |
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| Description | Purity ~90% (SDS-PAGE). Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells. Source: Recombinant protein corresponding to aa1-498 from human TCHP, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~77.1kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Mitochondrial protein with oncostatic activity, Mitostatin,Tumor suppressor protein |
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| Gene, Accession, CAS # | SwissProt: Q9BT92 |
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| Catalog # | 375509 |
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| Order / More Info | TCHP, Recombinant, Human, aa1-498, His-SUMO-Tag (Trichoplein Keratin Filament-binding Protein) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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