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| Product Name | TLR9, Fc Chimera, Recombinant, Mouse, aa26-818 (Toll-like Receptor 9, CD289) |
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| Description | Purity ~95% (SDS-PAGE under reducing conditions and visualized by silver stain). Endotoxin: ≤0.10EU/1ug (LAL). TLR9 (Tolllike receptor 9), designated CD289, is a member of the TLR family of innate immune receptors that is mainly expressed by colonic epithelium, CD123+ plasmacytoid predendritic cells (pDC), and splenic transitional B cells. TLR9 responds to unmethylated DNA CpG motifs that occur mainly in bacteria and viruses. Mouse TLR9 cDNA encodes a 1032 amino acid (aa) type I transmembrane glycoprotein with a 793aa extracellular domain (ECD) that contains 26 leucinerich repeats (LRRs, aa 26818), and a 193aa cytoplasmic domain with a TIR sequence that dimerizes with signaling adaptors such as MyD88. The mouse TLR9 ECD shares 87% aa sequence identity with rat and 71-74% with human, feline, canine, equine, porcine, bovine and ovine TLR9. Predicted splice forms vary at the N-terminus by initiating either upstream or downstream of the standard site. The full-length 150kD form, which i |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gene ID: 81897, Accession: AAK29625 |
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| Catalog # | 145847 |
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| Order / More Info | TLR9, Fc Chimera, Recombinant, Mouse, aa26-818 (Toll-like Receptor 9, CD289) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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