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| Product Name | sCD23, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). CD23 is a calcium dependent transmembrane glycoprotein which is expressed in many cell types. The cytoplasmic region of the protein has two isoforms the 'a' isoform that participates in IgE-regulated endocytosis, and the 'b' isoform, which is involved in IgE-regulated phagocytosis. It has been found that there are at least four soluble forms of the CD23 protein (sCD23) all of which are produced by the activity of metallo/cysteine proteases. In addition to binding IgE, sCD23 have been shown to promote the activation and differentiation of B-cells and stimulate the release of pro-inflammatory cytokines from monocytes. Source: Recombinant protein corresponding to human sCD23 expressed in E. coli. Molecular Weight: ~19.5kD Biological Activity: Measured by its ability to bind in a functional ELISA. Immobilized rhCD23 at 2ug/mL (100uL/well) can bind human IgE with a linear range of 0.0151ug/mL. Endotoxin: <1EU/ug (LAL) |
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| Size | 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | sCD23, Recombinant, Human (Low Affinity Immunoglobulin Epsilon Fc Receptor, BLAST-2, Fc-Epsilon-RII, Immunoglobulin E-Binding Factor, Lymphocyte IgE Receptor, CD23, B Cell Differentiation Antigen, C-type Lectin Domain Family 4 Member J, FCER2) |
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| Gene, Accession, CAS # | SwissProt: P06734 |
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| Catalog # | 500441 |
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| Order / More Info | sCD23, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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