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| Product Name | sCD23, Recombinant, Human (CD23 antigen, Fc-epsilon-RII, Lymphocyte IgE Receptor, BLAST-2) |
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| Description | Purity ~96% (SDS-PAGE). CD23, the low affinity receptor for IgE, belongs to the C-type lectin structural family and plays a role in the regulation of IgE synthesis and IgE mediated activities. It is found both as a transmembrane receptor protein and in a soluble form, which is generated by proteolytic cleavage of membrane bound CD23. The predominant soluble form of CD23 (sCD23) consists of 172aa corresponding to the extracellular domain of the full length precursor. sCD23, in addition to binding IgE, also exerts a number of IgE independent activities, such as promoting the activation and differentiation of B-cells and stimulating the release of pro-inflammatory cytokines from monocytes. Source: Recombinant protein corresponding to 172aa from soluble human sCD23, expressed in E. coli. Molecular Weight: ~19.2kD Biological Activity: Measured by its ability to induce TNF-alpha production by human PBMCs. Endotoxin: <0.1ng/ug of protein (<1EU/ug) AA Sequence: MELQVSSGFV CNTCPEKWIN FQRKCYYFGK |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CD23 antigen, Fc-epsilon-RII, Lymphocyte IgE receptor, BLAST-2 |
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| Gene, Accession, CAS # | CD23, Gene ID: 9606, SwissProt: Q30218 |
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| Catalog # | 220245 |
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| Order / More Info | sCD23, Recombinant, Human (CD23 antigen, Fc-epsilon-RII, Lymphocyte IgE Receptor, BLAST-2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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