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| Product Name | sCD22, Recombinant, Human |
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| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. CD22 is a B-lineage restricted 135kD glycoprotein whose cell surface expression is limited to resting and activated B lymphocytes.The physiological role of CD22 is still unknown.Targeted disruption of CD22 in mice results in a reduced level of surface IgM on peripheral B cells suggesting a role for CD22 in limiting antigen receptor signaling.CD22 is a member of the Ig gene superfamily that uniquely binds a sialic acid-dependent ligand.Recombinant human CD22 is a soluble 75.0kD protein which corresponds to the extracellular domain of CD22. Biological Activity: Determined by its ability to inhibit the proliferation of Raji cells. The expected ED50 for this effect is 10-17ug/ml. AA Sequence: SKWVFEHPET LYAWEGACVW IPCTYRALDG DLESFILFHN PEYNKNTSKF DGTRLYESTK DGKVPSEQKR VQFLGDKNKN CTLSIHPVHL NDSGQLGLRM ESKTEKWMER IHLNVSERPF PPHIQLPPEI QESQEVTLTC LLNFSCYGYP IQLQWLLEGV PMRQAAVTST SLTIKSVFTR SELKFSPQWS HHGKIVTCQL QDADGKFLSN DTVQLNVKHT PKLEIKVTPS DA |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143488 |
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| Order / More Info | sCD22, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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