| 产品详情 |
| Edit |   |
|---|
| Product Name | mitoNEET Inhibitor NL-1, Thiazolidinedione |
|---|
| Description | Purity ~98% (HPLC). A cell-permeable, thiazolidinedione (TZD) that acts as an inhibitor of MitoNEET (IC50=0.9uM) in competition with rosiglitazone and pioglitazone, in liver mitochondrial suspensions. In pharmacological studies, it was found to alter isolated mitochondrial complex I respiration with an IC50 of 2.4uM and inhibited State III respiration up to 45%. Furthermore, this compound (6-25uM) is shown to dose-dependently reduce lactate-dehydrogenase release in SH-SY5Y cultures, leading to a 40% decrease in rotenone-induced cell-death. Formula: C18H25NO3S Molecular Weight: 335.46 Solubility: DMSO (100mg/ml, clear, pale yellowish solution) |
|---|
| Size | 10mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | mitoNEET Inhibitor NL-1, Thiazolidinedione (5-(3,5-di-tert-butyl-4-hydroxybenzyl)-4-hydroxythiazol-2(5H)-one) |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 217556 |
|---|
| Price | |
|---|
| Order / More Info | mitoNEET Inhibitor NL-1, Thiazolidinedione from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|