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| Product Name | CD16, Recombinant, Human (Fc gamma RIII alpha, NK cells) |
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| Description | Purity ≥ 90%, as determined by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin: ≤ 1EU/1ug of the protein as determined by the LAL Method. Fcy RIIIa is a low/intermediate affinity receptor for polyvalent immune-complexed IgG. It is involved in phagocytosis, secretion of enzymes and inflammatory mediators, antibody-dependent cytotoxicity and clearance of immune complexes.1, 2 In humans, it is a 50-70kD type I transmembrane activating receptor expressed by NK cells, T cells, monocytes, and macrophages.1 Fcy RIIIb is highly related, sharing 97% amino acid (aa) identity within the extracellular domain (ECD), but is a GPI-linked receptor expressed on human neutrophils and eosinophils.1, 2 The ECD of Fcy RIIIa shares 63%, 61%, 65%, 59% and 58% aa identity with mouse Fcy RIV, rat Fcy RIIIa, feline CD16, bovine CD16 and porcine Fcy RIIIb paralogs, respectively. The Fcy RIIIa cDNA encodes 254 aa including a 16 aa signal sequence, 191 aa ECD with two C2-type Ig-like d |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C2267-31V |
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| Order / More Info | CD16, Recombinant, Human (Fc gamma RIII alpha, NK cells) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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