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| Product Name | ZAP70, Recombinant, Human, GST-Tag (Zeta Chain Associated Protein Kinase 70kD, SRK, STD, ZAP-70) |
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| Description | Purity ~70%-90% (Purified). ZAP70 is a non-receptor protein tyrosine kinase (part of the Syk/Zap70 family) that is involved in signaling by the T-cell antigen receptor (TCR). Ligation of the TCR/CD3 receptor in Jurkat T-cells induces phosphoprotein complexes which contain ZAP70. TCR zeta chains are initially phosphorylated by p56Lck that lead to the recruitment of ZAP70 via its SH2 domain. ZAP70 in turn phosphorylates other proteins in the TCR-phosphoprotein complex. One of the natural substrates for ZAP70 is the zeta-chain dimer of the TCR/CD3 complex. Source: Recombinant protein corresponding to human ZAP70, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~96kD Specific Activity: 113nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_001079 |
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| Catalog # | 500554 |
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| Order / More Info | ZAP70, Recombinant, Human, GST-Tag (Zeta Chain Associated Protein Kinase 70kD, SRK, STD, ZAP-70) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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