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| Product Name | IL-1alpha BioAssay™ ELISA Kit (Mouse) |
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| Description | IL-1 alpha and IL-1 beta are both synthesized as 31kD precursors that are subsequently cleaved into proteins with molecular weights of approximately 17,000. Neither precursor contains a typical hydrophobic signal peptide sequence and most of the precursor form of IL-1 alpha remains in the cytosol of cells, although there is evidence for a membrane-bound form of the precursor form of IL-1 alpha. The IL-1 alpha precursor reportedly shows full biological activity in the EL 4 assay. Among various species, the amino acid sequence of mature IL-1 alpha is conserved 60% to 70% and human IL-1 has been found to be biologically active on murine cell lines. Both forms of IL-1 bind to the same receptors, designated type I and type II. Recent evidence suggests that only the type I receptor is capable of signal transduction and that the type II receptor may function as a decoy, binding IL-1 and thus preventing binding of IL-1 to the type I receptor. Sample Type: Cell culture supernatants, serum, plas |
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| Size | 48 tests |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | IL-1alpha BioAssay™ ELISA Kit (Mouse) (Interleukin-1 alpha, IL-1 alpha, Hematopoietin-1, IL1A, IL1F1, IL1alpha, IL-1F1) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 360494 |
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| Order / More Info | IL-1alpha BioAssay™ ELISA Kit (Mouse) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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