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| Product Name | Thioredoxin 1 Blocking Peptide |
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| Description | Highly Purified. Peptide is used to block Thioredoxin 1 Rabbit mAb reactivity in immunohistochemistry protocols. Thioredoxin is a small redox protein found in many eukaryotes and prokaryotes. A pair of cysteines within a highly conserved, active site sequence can be oxidized to form a disulfide bond which is then reduced by thioredoxin reductase (1). Multiple forms of thioredoxin have been identified, including cytosolic thioredoxin 1 (Trx1) and mitochondrial thioredoxin 2 (Trx2). Thioredoxin participates in many cellular processes including redox signaling, response to oxidative stress and protein reduction (1). A potential role of thioredoxin in human disorders such as cancer, aging and heart disease is currently under investigation (2). Thioredoxin can play a key role in cancer progression, as it acts as a negative regulator of the proapoptotic kinase ASK1 (3) Changes in thioredoxin expression have been associated with meningococcal septic shock and acute lung injury (4,5). Quality |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | IHC N |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | T3792-10B |
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| Order / More Info | Thioredoxin 1 Blocking Peptide from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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