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Product Name | BRD 6989 |
Description | Binds and inhibits Cdk8 in complex with cyclin C (IC50 ~ 200 nM). Enhances IL-10 production in activated human and murine macrophages and dendritic cells (EC50 is approximately 1 μM for IL-10 production in bone marrow-derived dendritic cells). Also inhibits CDK19 in complex with cyclin C. Purity 98%. MW (observed): 264.33 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2-Amino-5,6,7,8-tetrahydro-6-methyl-4-(3-pyridinyl)-3-quinolinecarbonitrile |
Gene, Accession, CAS # | CAS: 642008-81-9 |
Catalog # | 6438/50 |
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Order / More Info | BRD 6989 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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