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Product Name | Brefeldin A |
Description | Reversible inhibitor of protein translocation from the endoplasmic reticulum (ER) to the Golgi apparatus. Blocks binding of ADP-ribosylation factor to the Golgi apparatus and inhibits GDP-GTP exchange. Can be used to induce autophagy in mammalian cells. Also enhances CRISPR-mediated homology-directed repair (HDR) efficiency ~2-fold when applied at 100 nM, in human induced pluripotent stem cells (iPSCs). Purity 98%. MW (observed): 280.36 |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1,6,7,8,9,11aβ,12,13,14,14αa-Decahydro-1β,13α-dihydroxy-6β-methyl-4H-cyclopent(f)oxacyclotridecin-4-one |
Gene, Accession, CAS # | CAS: 20350-15-6 |
Catalog # | 1231/5 |
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Order / More Info | Brefeldin A from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 21187068, 24266887, 24501347, 24783958, 29212034 |
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