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| Product Name | Brequinar sodium |
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| Description | Potent and selective dihydroorotate dehydrogenase (DHODH) inhibitor (IC50 = ~20 nM). Causes depletion of pyrimidine nucleotides. Exhibits minimal inhibition against a panel of >400 kinases. Triggers differentiation of AML cell lines (ED50 = ~ 1 μM. Note uridine concentration effects ED50 value). Causes differentiation and depletion of leukemia-initiating cells in vivo. Antimetabolite. Purity 99%. MW (observed): 397.35 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-Fluoro-2-(2'-fluoro[1,1'-biphenyl]-4-yl)-3-methyl-4-quinolinecarboxylic acid sodium. BRQ, DuP 785, NSC 368390 |
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| Gene, Accession, CAS # | CAS: 96201-88-6 |
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| Catalog # | 6196/10 |
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| Price | |
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| Order / More Info | Brequinar sodium from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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