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Product Name | DPO-1 |
Description | Blocker of IKur ultrarapid delayed rectifier potassium current and KV1.5 channels (IC50 = 0.31 μM for rKV1.5). Displays selectivity for inhibition of IKur over Ito (8-fold), IK1, IKr and IKs (20-fold) in native myocytes and selectivity for rat recombinant KV1.5 over KV3.1 (~ 15-fold). Increases action potential duration in atrial but not ventricular myocytes and prevents atrial arrhythmia. Purity 99%. MW (observed): 340.44 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | [1S-(1α,2α,5β)]-[5-Methyl-2-(1-methylethyl)cyclohexyl]diphenylphosphine oxide. Diphenyl phosphine oxide-1 |
Gene, Accession, CAS # | CAS: 43077-30-1 |
Catalog # | 2533/50 |
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Order / More Info | DPO-1 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 19857498, 23717641, 24797243, 25435365 |
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