| 产品详情 |
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| Product Name | dTRIM 24 |
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| Description | PROTAC composed of the TRIM24 ligand IACS-9571 conjugated to a VHL ligand. Displays dose- and time-dependent degradation of TRIM24 in cells, with maximum degradation achieved at 5 μM. Degradation phenotypically mirrors genetic deletion of TRIM24. Demonstrates antiproliferative effects in MOLM-13 cells. Cell permeable. Purity 98%. MW (observed): 1113.3 |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2S,4R)-1-((S)-15-(tert-Butyl)-1-(3-(N-(1,3-dimethyl-2-oxo-6-(3-propoxyphenoxy)-2,3-dihydro-1H-benzo[d]imidazol-5-yl)sulfamoyl)phenyl)-1,13-dioxo-5,8,11-trioxa-2,14-diazahexadecan-16-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxami |
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| Gene, Accession, CAS # | CAS: 2170695-14-2 |
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| Catalog # | 6607/5 |
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| Price | |
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| Order / More Info | dTRIM 24 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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