产品详情 |
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Product Name | IC 261 |
Description | ATP-competitive casein kinase 1 (CK1) inhibitor. Displays >15 fold selectivity for CK1δ and CK1ε over CK1α (IC50 values are approximately 1 μM for CK1δ and CK1ε and 16 μM for CK1α). Arrests cell cycle at postmitotic G1 phase in cells expressing p53. Inhibits CK1 mediated phosphorylation of LRRK2 in cell lines. Purity 98%. MW (observed): 311.33 |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1,3-Dihydro-3-[(2,4,6-trimethoxyphenyl)methylene]-2H-indol-2-one |
Gene, Accession, CAS # | CAS: 186611-52-9 |
Catalog # | 6676/25 |
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Order / More Info | IC 261 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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