产品详情 |
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Product Name | ICA 069673 |
Description | Selective KV7.2/KV7.3 (KCNQ2/3) channel opener (EC50 = 0.69 μM). Exhibits 20-fold selectivity for KV7.2/KV7.3 over KV7.3/KV7.5, with no measurable activity over a panel of cardiac ion channels. Hyperpolarizes resting membrane potential and inhibits spontaneous action potentials in guinea pig detrusor muscle (DSM) isolated cells. Orally active in animal models of epilepsy. Purity 99%. MW (observed): 269.63 |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-(2-Chloro-5-pyrimidinyl)-3,4-difluorobenzamide |
Gene, Accession, CAS # | CAS: 582323-16-8 |
Catalog # | 4305/5 |
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Order / More Info | ICA 069673 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 24944189, 27263036 |
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