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Product Name | SAR 7334 |
Description | Potent TRPC6 inhibitor (IC50 values are 9.5, 226 and 282 nM for TRPC6, TRPC7 and TRPC3-mediated Ca2+ influx). Exhibits no significant activity at TRPC4 and TRPC5 channels. Suppresses TRPC6-dependent acute hypoxic pulmonary vasoconstriction (HPV) in the isolated perfused mouse lung. Orally bioavailable. Purity 98%. MW (observed): 440.79 |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4-[[(1R,2R)-2-[(3R)-3-Amino-1-piperidinyl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chlorobenzonitrile dihydrochloride |
Gene, Accession, CAS # | CAS: 1333207-63-8 |
Catalog # | 5831/5 |
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Order / More Info | SAR 7334 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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